摘要
目的:评价活血化瘀中药复方治疗慢性前列腺炎的疗效和安全性。方法:全面检索截至2006年12月活血化瘀中药复方治疗慢性前列腺炎的随机对照试验,运用Jadad量表和试验分配隐藏评价纳入文献的方法学质量并提取有效数据进行Meta-分析,用RevMan 5.0软件完成统计和系统评价。结果:共9篇文献包含1815例患者符合纳入标准。前列安通片(对比舍尼通)与自拟复方(对比前列康)具有改善慢性前列腺炎患者前列腺炎症状评分的效应(P<0.02、0.00001);对比前列康,前列腺胶囊、前列腺汤、自拟复方均具有改善患者疼痛与排尿不适的作用(P值均<0.00001),与前列速康宝片、丹蒲胶囊(对比前列泰片)也均能使患者异常的按摩前列腺液白细胞计数(EPS-WBC)恢复正常(P值均<0.00001与<0.006、<0.03)。结论:活血化瘀类中药复方在改善慢性前列腺炎患者的症状、前列腺液指标可能优于前列康、舍尼通及前列泰片。
Objective To evaluate the efficacy and safety of Chinese medicine of activating blood circulation and dispelling blood stasis in treating patients with chronic prostatitis Methods Randomized clinical trials comparing herbs of activating blood circulation and dispelling stasis versus plant amedica, other herbal medicine and western medicine treatments in the treatment of chronic prostatitis were identified by electronic and manual search. The methodological quality of the included trials was assessed and Meta - analysis was performed with Revman 4.2 software. Nine randomized clinical trials（n = 1815） were identified. Results The methodological quality ranked high in one RCT and the other ranked low. Meta- analysis indicated that Qianlieantong（前列安通） versus Prostat and a compound Chinese medicine of activating blood circulation and dispelling stasis versus Qlanhekang（ 前列康）, were effective on reducing CP- SI of patients （P 〈 0.02, 0.000 01）. Comparing with Qianliekang, Qianliexian（前列腺） capsule, Qianliexian decoction, the compound activating blood circulation and dispelling stasis herbs was more effective on reducing ache and urinating symptoms （ P 〈 0.000 01 ）. Furthermore, Qianliesukangbao（前列速康宝 ） tablets, Danpu（丹蒲） capsules versus Qianlietaiplan（前列泰） tablets were more effective on restoring normal counts of EPS - WBC （ P 〈 0. 000 1 and 〈 0. 006,0.03）. Conclusion Herbs of activating blood circulation and dispelling stasis may be effective in the treatment of chronic prostatitis.
出处
《中国中西医结合外科杂志》
CAS
2008年第6期532-536,共5页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
前列腺炎
中药
活血化瘀
META-分析
prostatitis, Chinese herb of activation blood circulation and dispelling stasis, Meta- analysis
