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婴幼儿亚临床甲状腺功能减退症诊断治疗和随访——附107例临床分析 被引量:5

Diagnosis, therapy and follow-up in infants with subclincal hypothyroidism A clinical analysis of 107 cases
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摘要 107例患儿经1—8次检查后血清TSH值均〉20mlU/L,血FT4、TT4值在正常低值范围,治疗4周后复查,血TSH明显下降,血FT4、TT4值较前升高(均P〈0.01)。甲状腺B超检查7例(6.54%)显示甲状腺发育不良,7例(6.54%)甲状腺肿大血流丰富,93例(86.91%)位置大小形态无异常。左旋甲状腺素初始剂量以3—4μg·kg^-1·d^-1为宜。 The serum TSH levels of 107 infants with subclinical hypothyroidism (SH) were 〉20 mIU/L after 1-8 check-up, along with FT4, TT4 within low normal range. After given small dosage L-T4 for 4 weeks, blood TSH level obviously descended while FT4, TT4 ascended ( all P 〈0.01 ). Seven cases of thyroid hypogenesis and 7 strumas were found by uhrasonography. It seems appropriate to use dosage of 3-4 μg·kg^-1·d^-1 L-T4 in treating SH.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2008年第6期637-638,共2页 Chinese Journal of Endocrinology and Metabolism
基金 浙江省卫生厅基金资助项目(项目编号:20058101)
关键词 甲状腺功能减退症 婴幼儿 治疗 随访研究 Hypothyroidism Infants Therapy Follow-up studies
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