5Sunshine A,Olson NZ,Colon A,et al.Analgesic efficacy of controlled-release oxycodone in postoperative pain[J].J Clin Pharmacol,1996,36(7):595~603
6Mandema JW,Kaiko RF,Oshlack B,ct al.Characterization and validation of a pharmacokinetic model for controlled-release oxycodone[J].BrJ Clin Pharmacol,1996,42(6):747~756
7Hagen NA,Babul N.Comparative clinical efficacy and safety of a novel controlled-release oxycodone formulation and controlledrelease hydromorphone in the treatment of cancer pain[J].Cancer,1997,79(7):1428~1437
8Heiskanen T,Kalso E.Controlled-release oxycodone and morphine in cancer related pain[J].Pain,1997,73(1):37~45
9Bruera E,Belzile M,Pituskin E,et al.Randomized,double-blind,cross-over trial comparing safety and efficacy of oral controlled-release oxycodone with controlled-relea se morphine in patients with cancer pain[J].J Clin Oncol,1998,16 (10):3222~3229
10Kaplan R,Parris WC,Citron ML,et al.Comparison of controlled-release and immediate-release oxycodone tablets in patients with cancer pain[J].J Clin Oncol,1998,16(10):3230~3237