摘要
目的通过探讨胎儿生长受限脐血中甲状腺激素的变化,探讨其发病机制以提出新的治疗方法。方法采用化学发光免疫分析法,测定正常足月妊娠30例和足月妊娠FGR 30例脐血及母体中甲状腺素(T4)、三碘甲状腺原氨酸(T3)、游离T3(FT3)、游离T4(FT4)、促甲状腺素(TSH)水平。结果FGR组脐血以及母体中T4、FT4显著下降(P<0.01),TSH明显升高(P<0.01)。结论低甲状腺素水平可能是FGR的发病因素之一。
Objective： To investigate the chafiges of thyroid hormone levels of umbilicus blood in the fetal growth restriction. Methods ： The concentration of triiodothyronine （ T3 ）, Thyroxine （ T4）, Free T3 （ FT3 ） , Free T4 （ FT4 ）, Thyroid Stimulating Hormone （TSH） were tested in the umbilicus blood and pregnant womens blood of 50 normal term infancy by radioimmunology （ control group） and 30 cases of fetal Growth Restriction （FGR group） respectively. Results： T4 in umbilical blood and pregnant women＇s blood was lower in FGR group than that in control group （ P 〈0.01 ）, the TSH level in umbilical blood and pregnant women＇s blood was higher in FGR than that in control group （ P 〈 0.01 ）. Conclusion： This study confirmed that functional decay of thyroid might play an important role in the pathogenesis of FGR. Restriction ; FGR; T3 ; T4 ; FT3, FT4, TSH.
出处
《中国优生与遗传杂志》
2008年第11期50-51,共2页
Chinese Journal of Birth Health & Heredity
