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原发性高血压病24小时平均脉压与靶器官损害关系探讨

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摘要 目的探讨24h平均脉压(24hPP)与原发性高血压患者靶器官损害的关系。方法选择187例原发性高血压患者行24h动态血压监测,根据24hPP水平分为A组(24hPP〈40mmHg)、B组(40~50mmHg)、C组(50~60mmHg)、D组(60mmHg≤24hPP)四组,行超声心动图及24小时尿微量白蛋白定量检查。结果高血压患者,随着24hPP水平的增宽,左心室心肌质量指数(LVMI)增加、左心室射血分数(LVEF)降低、左心室舒张早期和晚期最大血流速度的比(E/A)值减少、E峰减速时间(DT)值增加,24小时尿微量蛋白增多(P〈0.05-0.01)。结论24hPP对左心室功能损害及肾功能损害有预测价值,高血压病患者随着24hPP增宽更易导致左心室肥厚、左心室收缩舒张功能减退及肾功能损害。
作者 王虹
出处 《心脑血管病防治》 2008年第6期386-388,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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参考文献9

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