摘要
（目的〕探索非小细胞肺癌的化疗方式。〔方法）对30例病人采用三苯氧胺、异博定加MFP方案（甲组）化疗，并随机与采用CAP或IEP方案（乙组）的30例病人进行比较。［结果〕两级总有效率分别为43.3％和26．7％；甲级毒副反应轻微，生活质量明显改各，一年生存率提高，统计学处理差异有显著性（P＜0．05）、〔结论）使用三苯氧胺、异搏定加MFP方案治疗非小细胞肺癌具有临床探讨价值。
(Purpose) To explore the effect of tamoxifen, verapamil and MFP combined chemotherapy for non-small cell lung cancer(NSCLC). (Methods) Sixty patients with NSCIC were randomized to 2 treatment groups: tamoxifen, verapamil and MFP combination chemotherapy(group A), CAP regimen or IEP regimen comination chemetherapy(group B). Their response rates were compared. (Results) By means of comparsion, the overall response rate(CR+ PR) of group A was 43. 3% (13/30) and that of group B was 26. 7% (8/30). Toxicity effec of chetnoherapy in group A was slight and quaity of life was better than that of group B 1-year survival rate of group A was 60. 0% (18/30), group B 23. 3% (7/30). The statistical edpeis showed marked significant difhant(P＜0. 05). (Concluaions) The results showed that tamoxifen, verapamil combined with MFP chmotherapy for non-small cell lung cancer is effeclive.
出处
《浙江肿瘤》
CAS
1998年第1期26-27,共2页
