摘要
目的：为了探讨降钙素治疗腰椎管狭窄伴间歇性跛行（ＮＩＣＬ）的疗效及作用机制。方法：应用鳗鱼降钙素对３１例腰椎管狭窄伴间歇性跛行患者进行治疗。结果：治疗４周后７２％患者的步行能力提高，下肢疼痛症状减轻；８周后８３％患者的步行能力明显提高，相伴出现的下肢痛亦有所改善。结论：认为降钙素不仅能迅速有效地缓解骨质疏松骨痛，而且可有效地提高腰椎管狭窄伴间歇性跛行患者的步行能力，改善神经功能，其作用机制可能是由于降钙素能增加马尾神经组织的血供。
Aim:Studying the mechanism and clinical effect of calcitonin treatment on lumbar spinal canal stenosis with NICL.Methods:31 cases with neurogenic intermittent claudication were treated with calcitonin for 8 weeks.Results:After 4 weeks,considerable increase in walking distance and calf pain relief were observed in 72%patients.At the end of 8 weeks,83% cases responded with remarkable improvement in their walking distance and legs pain.Conclusion:The calcitonin not only provided beneficial effect to patients who had pain with osteoporosis,but also supplied considerable improved to patients who had symptoms of neurogenic claudication with lumbar spinal canal stenosis.The mechanism of this effect seems that calcitonin increases cauda equina blood flow.
出处
《颈腰痛杂志》
1998年第1期8-10,共3页
The Journal of Cervicodynia and Lumbodynia
关键词
腰椎管狭窄
间歇性跛行
降钙素
治疗
Lumbar spinal canal stenosis Neurogenic intermittent claudication Calcitonin
