摘要
目的探讨下呼吸道院内真菌感染的危险因素及治疗方法。方法回顾性分析我院2003年1月至2007年12月收治的下呼吸道院内真菌感染126例，对其临床资料、病原体分布、诊断及治疗进行临床分析。结果：126例患者念珠菌感染率89．68％（113／126），其中白色念珠菌50．79％（64／126），光滑念珠菌11．90％（15／126），克柔念珠菌9．52％（12／126），热带念珠菌8．73％（11／126）；其次烟曲霉菌感染率6．35％（8／126）。本组病例病死率13．49％（17／126）。结论长期应用广谱抗生素、糖皮质激素、细胞毒素及免疫抑制剂是继发真菌感染的重要原因。早预防、早诊断、早治疗是控制院内下呼吸道真菌感染的关键。因此对于高危患者，一旦拟诊下呼吸道真菌感染存在，就应采取早期经验性抗真菌治疗。
Objective To investigate the risk factors of lower respiratory tract fungal infection in hospital. Methods The clinical materials of 126 patients infected with candida from January 2003 to June 2007 were retrospectively analyzed about the etiological factor, diagnosis and treatment. Results One hundred and thirteen strains of candida were cultivated from in 126 patients. The infection rate of candida albicans was as high as 50.79 % （64/126） . the infection of glabrata and krese covered a percentage of 11.90% （15/126） and 9.52% （12/126） ,tropicalis 8.73% （11/126） .respectively. The mortality rate was 13.49%. Conclusions Long - term application of broad - spectrum antibiotic usag or cytotoxic agent and the degression of immunity in patients are the important reasons for the secondary fungal infection in bronch -lung. In order to get a satisfactory rapeutic effect, early precaution, early diagnosis, early treatment.is important. So select the suitable antifungal agent should been done for the patients may be accompany with fungal infection of lower respiratory tract.
出处
《中国实用医刊》
2009年第1期26-27,共2页
Chinese Journal of Practical Medicine
关键词
下呼吸道
院内真菌感染
诊断
治疗
Lower respiratory tract
Fungal infection in hospital
Diagnosis
Teatment
