摘要
为了比较腹腔镜胆囊切除术（ＬＣ）和开腹胆囊切除术（ＯＣ）对组织的损伤程度，选择拟行单纯胆囊切除术的患者４０例，分别行ＬＣ和ＯＣ各２０例，用酶联免疫法测定术前２４小时、术后１２、２４及４８小时血清白细胞介素－６（ＩＬ－６）；用散射比浊法测定术前２４小时、术后１２、２４及４８小时血清Ｃ－反应蛋白（ＣＲＰ）。结果显示：两组患者术前２４小时血清ＩＬ－６和ＣＲＰ水平相近（Ｐ＞０．０５）；术后１２、２４及４８小时ＯＣ组血清ＩＬ－６和ＣＲＰ水平分别高于ＬＣ组（Ｐ＜０．０５）；术后４８小时ＬＣ组血清ＩＬ－６和ＣＲＰ降至术前水平（Ｐ＞０．０５），但ＯＣ组仍高于术前水平（Ｐ＜０．０５）。ＯＣ组平均手术时间、切口长度及术后平均住院日均比ＬＣ组长（Ｐ＜０．０５）。结果表明：ＬＣ组织损伤程度比ＯＣ小，而后者平均手术时间和切口长度较长是血清ＩＬ－６和ＣＲＰ反应水平较高的主要原因。
With indication for elective cholecystectomy,40 patients were randomized into laparoscopic cholecystectomy (LC,n=20) and open cholecystectomy (OC,n=20) to observe the damage inflicted upon by LC and OC.Serum interleukin6 (IL6) and Creactive protein (CRP) tests were carried out respectively by ELISA and nepheloturbidity 24 hours before and 12,24 and 48 hours after surgery.Results demonstrated that no intergroup difference in IL6 and CRP concentration was detected before surgery.However the levels of both tests in OC increased more than that in LC at 12,24 and 48 hours postoperatively (P<005).IL6 and CRP in LC group restored to preoperative standards 48 hours after the insult while that in OC remained still hither (P<005) indicating that the damage of tissues by LC is less than OC,i.e. The operative duration is shorter and incisional injury lighter exerted by LC.
出处
《中华消化内镜杂志》
1998年第2期72-74,共3页
Chinese Journal of Digestive Endoscopy
关键词
腹腔镜
胆囊切除术
开腹
白细胞介素6
CRP
Laparoscopic cholecystectomy
Open cholecystectomy
Interleukin6
Creactive protein
