摘要
目的:评价小剂量肝素对冠状动脉造影(CAG)术的可行性和安全性。方法;将150例择期行CAG的病人随机分为常规肝素组(即动脉鞘管置入后经鞘管给予肝素3000IU);无肝素组(鞘管及造影导管均于体外用肝素生理盐水冲洗);小剂量肝素组(即动脉鞘管置入后经鞘管给予肝素1000IU);观察CAG期间及其后48小时内病人发生卒中、新发生的外周动静脉血栓、穿刺与非穿刺部位出血、假性动脉瘤与动静脉瘘、死亡等并发症情况。结果:常规肝素组出血并发症较另外两组明显增加(P<0.05);而无肝素组则较易出现栓塞并发症;小剂量肝素组出血并发症低,无栓塞并发症发生,卧床时间缩短、痛苦小等优点。结论:小剂量肝素对CAG术是安全的、可行的。
Objective： To evaluate the feasibility mad＇safety of-low-dose heparin on coronary artery angiography. Methods： 150 accepted elective coronary artery angiography patients were divided into three groups named convention heparin group （inject heparin 3000IU in artery from the artery pipeline）, no heparin group （the pipeline and the apparent pipe were washing with the sodium chloride injection before coronary artery angiography）and the low-dose heparin group （inject heparin 1000IU in artery from the artery pipeline） randomly. To investigate the complication of stroke,new thrombus in peripheral artery and vein hemorrhage at the artery puncture site and non-puncture site, artery and vein fistula, psandoaneurysm at the puncture site and die were observed from the time of inserting the sheath into the artery in 48 hours after coronary artery angiography. Results： The complication of hemorrhage of the convention heparin group were more increased than the other two groups （P〈0.05）. The complication of jam of no heparin group was easily happen. The complication of hemorrhage of low-dose heparin was less than the other two groups and no corupliealion of jam was found. Conclusion： Coronary artery angiography low-dose heparin was safe anti feasible.
出处
《中国医药导刊》
2008年第9期1375-1376,共2页
Chinese Journal of Medicinal Guide
关键词
冠状动脉造影术
肝素
并发症
coronary artery angiography
heparin
complication
