摘要
气道重塑是支气管哮喘的病理特征之一，成功复制支气管哮喘的动物模型是研究支气管哮喘反复难愈的关键。大鼠、小鼠、豚鼠是国内试验中最常选用的实验动物。本文筛选了发表于国内杂志上25篇可信度较高的关于支气管哮喘气道重塑模型建立的实验研究，对其进行分析评价，总结出国内复制支气管哮喘气道重塑动物模型的特点，为研究人员对实验方法的选择提供一定的借鉴。
Airway remolding is one of the pathological characteristics in bronchial asthma patients. It is critical to successful copy asthma animal model and study the reason why asthma is hard to treat. Rat, mouse and guinea pig are the most common experimental animals in China. 25 articles about animal model in asthma airway remolding which were published in domestic journals were select, analysis, evaluate. Some characteristics were found. It maybe gives some good advice to researchers.
出处
《医学综述》
2009年第1期14-18,共5页
Medical Recapitulate
基金
首都医学发展科研基金资助(2005-8F-Ⅱ-029)
关键词
支气管哮喘
气道重塑
动物模型
Bronchial asthma
Airway remolding
Animal model
