摘要
目的观察金连油的抗炎消肿、抗烫伤作用。方法用二甲苯致小鼠耳肿胀、甲醛致小鼠足跖肿胀法观察金连油的抗炎作用;用100℃铁片制作小鼠实验性烫伤模型,观察金连油的抗烫伤作用。结果金连油3个剂量(原药、1/2原药和1/4原药)均能抑制小鼠耳仲胀度,金连油原药和1/2原药能抑制小鼠足跖肿胀度和缩小小鼠烫伤后的早、中期伤口面积,并且均表现出一定的量效关系。结论金连油具有明显的抗炎和抗烫伤作用。
OBJECTIVE Anti-inflammator and anti-scalds action of Jing-lian oil was observed. METHODS Using auricle-edema-model induced by dimethylbenzene and ankle-edema-model induced by formaldehyde in mice to observe anti-inflammator action of Jing-lian oil;Using model scalds induced by 100℃ iron sheet to observe antiscalds action of Jing-lian oil. RESULTS Three dose of Jing-lian oil （original fluid, 1/2 original fluid and 1/4 original fluid） could suppress mouse ear swelling. The original fluid and 1/2 original fluid could suppress mouse ankle swelling and reduce mouse scald and displays certain dose-dependent manner. CONCLUSION Jing-lian oil has obvious anti-inflammator and anti-scalds functions.
出处
《海峡药学》
2008年第12期28-29,共2页
Strait Pharmaceutical Journal
关键词
金连油
抗炎
抗烫伤
小鼠
Jing-lian oil
Anti-inflammator
Anti-scalds
Mouse
