摘要
目的探讨急性心肌梗塞(AMI)后压力反射敏感性(BRS)的临床意义。方法分析31例AMI患者和17例正常对照组的BRS、心率变异以及临床情况。结果AMI患者3周BRS明显小于17例正常对照组(10.7±7.2ms/mmHgvs.4.2±1.5ms/mmHg,P<0.05);心肌梗塞患者随访中猝死2例,其BRS降低最明显;心梗患者的BRS与心率变异各项指标无相关性,与年龄、性别、超声射血分数、心肌酶谱等也无相关性;BRS有较大个体差异。结论BRS在心肌梗塞患者明显下降,并可作为患者的一项独立的预后指标;BRS与心率变异是反映患者自主神经的二个不同方面。
Objective To analyze the baroreflex sensitivity (BRS) and its clinical significance.Methods The baroreflex sensitivity, heart rate variability and clinical situation of 31 patients with acute myocardial infarction (AMI) and 17 normal controls were studied.Results BRS of the patients in the third week after AMI was much lower than that of the normal controls (4.2±1.5ms/mmHg vs 10.7 ±7.2 ms/mmHg, P <0 05). Two patients had sudden death during the follow up, and their BRS were the lowest. BRS of the patients had differences between each other and overlapped with that of normal controls. It had no correlation with heart rate variability, age, sex, left ventricular ejective fraction or serum peak creatine kinase.Conclusion BRS of the AMI patients was lower than that of the normal controls, and was associated with the prognosis, and BRS and heart rate variability were two aspects of the autonomic nervous system.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
1998年第1期51-52,共2页
Chinese Journal of Cardiology
关键词
心肌梗塞
AMI
压力反射敏感性
baroreflex sensitibity sudden death, cardiac myocardial infarction heart rate variability