摘要
目的通过贵州省毕节市燃煤型地方性氟中毒地区汉族人群血常规调查,了解其健康状况及所存在问题。方法在贵州省毕节市燃煤污染型地氟病病区,对已改良炉灶的长春镇长春村的全体居民(干预组)和未改良炉灶的鸭池镇十八村的全体居民(非干预组)进行血常规检查,检查指标包括白细胞(WBC)、红细胞(RBC)、血红蛋白(Hb)、红细胞压积(HCT)、红细胞平均压积体积(MCV)、平均红细胞血红蛋白(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞体积分布宽度(RDW—CV)、血小板(PU)。结果在男性中,干预组RBC、Hb、HCT、MCHC、PLT分别为(4.95±1.18)×10^12/L、(138.46±15.90)g/L、(50.19±11.48)%、(284.90±48.73)g/L、(334.92±119.34)×10^9/L,非干预组分别为(4.02±0.47)×10^12、(131.00±35.90)g/L、(40.90±7.60)%、(323.34±41.95)g/L、(280.79±100.34)×10^9/L,组间比较差异均有统计学意义(U值分别为7.72、3.50、7.12、6.28、3.66,P〈0.03.);在女性中,干预组RBC、HCT、MCV、MCH、MCHC、RDW~CV、PLT分别为(4.75±1.20)×10^12(46.914.-11.20)%、(99.30±6.88)fl、(28.30±8.66)Pg、(275.63±54.49)g/L、(16.95±1.63)%、(351.23±150.37)×10^9/L,非干预组分别为(3.85±0.65)×10^12、(38.80±6.60)%、(100.80±7.00)fl、(33.10±5.40)Pg、(327.34±44.52)g/L、(16.60±1.58)%、(279.40±98.07)×10^9/L,组间比较差异有均统计学意义(U值分别为8.92、10.72、2.04、6.61、9.82、2.06、5.39,P〈0.01或〈0.05)。非干预组的RBC和Hb异常率[32.62%(92/282)、16.67%(47/282)]高于干预组[9.73%(29/298)、6.73%(20/298)],组间比较差异均有统计学意义(x2值分别为45.992、14.054,P〈0.01)。结论氟中毒病区干预组人群血常规检查情况优于非干预组,尤其是干预组的贫血情况改善较好。
Objective To carry on a survey on blood routine examination of coal-burning endemic fluorosis population in Bijie City, Guizhou Province in order to study their health status and problems. Methods Blood routine examination was performed in the residents in coal-fired pollution endemic fluorosis-endemic area, including the residents of the Changehun Village of Changeun Town(intervention group) whose stoves had been improved and of Shiba Village Yachi Town not improved in Bijie City, Guizhou Province. The indicators were including leukocyte (WBC), red blood eell(RBC), hemoglobin(Hb), hematoerit(HCT), the average hematoerit red blood cell volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width-CV(RDW-CV), platelets(PLT). Results RBC, Hb, HCT, MCHC, PLT were (4.95 ± 1.18) ×10^12/L, (138.46 ± 15.90) g/L, (50.19 ± 11.48)%, (284.90 ± 48.73 )g/L, (334.92 ± 119.34) ×10^9/L for the male in the intervened group, and they were (4.02 ± 0.47) ×10^12/L, (131.00 ± 15.90)g/L, (40.90 ± 7.60)%, (323.14 ± 41.95)g/L, (280.79 ± 100.34) ×10^9/L in non-intervention group, respectively. Inter-group comparison, the difference was statistically significant (U = 7.72,3.50,7.12,6.28,3.66, P 〈 0.01 ). RBC, HCT, MCV, MCH, MCHC, RDW-CV, PLT were respectively(4.75 ± 1.20) ×10^2/L, (46.91 ± 11.20)%, (99.30 ± 6.88)fl, (28.10 ± 8.66)pg, (275.61 ± 54.49)g/L, (16.95 ± 1.63)%, (351:23 ± 150.37) ×10^9/L for the female in the intervened group, and were (3.85 ± 0.65) ×10^~2/L, (38.80 ± 6.60)%, (100.80 ± 7.00)fl, (33.10 ± 5.40)pg, (327.14 ± 44,52)g/L, (16.60 ± 1.58)%, (279.40 ± 98.07) ×10^9/L in the group un-intervened. Inter-group comparison found that there was a significant difference(U = 8.92,10.72,2.04,6.61,9.82,2.06,5.39, P 〈 0.001 or 0.05) and the abnormal rate of RBC and Hb in non-intervention group [ 32.62% (92/282) , 16.67% (47/282) ] was higher than that in the intervention group[9.73%(29/298),6.71%(20/298), X2= 45.992,14.054, P 〈 0.01 )3. Conclusion Experiment group has better results of blood routine test compared to non-intervention group, especially of anemia.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2009年第1期94-96,共3页
Chinese Jouranl of Endemiology
基金
基金项目:科技部973项目(2006CB708513)
国家自然科学基金(30760224)
贵州省科技厅项目[黔科合外G字(2006400107)、黔省专合字(2006)52、黔科合重大专项(2006)6015]
关键词
氟化物中毒
血细胞
诊断试验
常规
Fluoride poisoning
Blood cells
Diagnostic tests, routine