摘要
目的:探讨乳腺癌钼靶X线表现有钙化与c-erbB-2癌基因蛋白表达之间的相关性。方法:收集术前行钼靶X线检查且临床资料完整的乳腺癌患者144例,术后病理标本经免疫组织化学染色判断c-erbB-2表达情况。将钼靶X线表现分为有无钙化与c-erbB-2表达状况进行比较研究。结果:144例乳腺癌患者中,有钙化组c-erbB-2阳性率(51.85%)高于无钙化组(33.33%),差异有统计学意义,χ2=4.812,P=0.028。结论:乳腺癌钼靶X线征像在一定程度上反映了c-erbB-2的表达状况。
OBJECTIVE： To verify the correlation between calcification in molybdenum target mammography and the expression of c erbB-2 in breast cancer. METHODS： A total of 144 cases of breast cancer confirmed histologically were examined with mammography before operation,and the expression of c-erbB-2 in all mastectomy specimens were measured by immunohistochemistry. The mammographic feature calcification was studied comparatively with the c-erbB-2 expression. RESULTS： In the 144 cases of breast cancer, the c-erbB-2 positive rate in lesions with calcification was statistically higher than that in lesions without calcification （51.85% vs 33.33%, X^2=4. 812, P=0. 028）. CONCLUSION： The molybdenum target mammographic features of breast cancer can reflect the expressive state of c-erbB-2 to a certain degree.
出处
《中华肿瘤防治杂志》
CAS
2008年第19期1481-1482,共2页
Chinese Journal of Cancer Prevention and Treatment
