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细胞外基质金属蛋白酶诱导因子与急性冠脉综合征关系的研究进展 被引量：3

Relationship Between Extracellular Matrix Metalloproteinases Inducer and Acute Coronary Syndrome
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摘要 细胞外基质金属蛋白酶诱导因子是一种高糖基化的跨膜蛋白,广泛表达于人体的各种组织细胞,属于免疫球蛋白家族。细胞外基质金属蛋白酶诱导因子可通过刺激冠脉动脉粥样斑块内的基质金属蛋白酶的分泌来影响斑块的稳定性,在急性冠脉综合征的发生、发展方面起到了重要作用。现就细胞外基质金属蛋白酶诱导因子在急性冠脉综合征方面的作用作一综述。 Extracellular matrix metalloproteinases inducer （EMMPRIN ）, a highly glycosylated transmemebrane glycoprotein, is a member of the immunoglobulin family that is expressed widly in human tissue cells. EMMPRIN can influence plaque stability through stimulating the secretion of matrix metalloproteinases in coronary artery atherosclerotic plaque, which play an important role in acute coronary syndrome （ ACS ） genesis and development. This article reviews the role of EMMPRIN in ACS.
作者 叶金善 郭瑞威 杨丽霞
机构地区 成都军区昆明总医院心内科
出处 《心血管病学进展》 CAS 2009年第1期182-184,共3页 Advances in Cardiovascular Diseases
关键词 细胞外基质金属蛋白酶诱导因子 基质金属蛋白酶 急性冠脉综合征 extracellular matrix metalloproteinases inducer matrix metalloproteinases acute coronary syndrome
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献20

  • 1Decastro R, Zhang Y, Guo H, et al. Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer [ J ]. J Invest Dermatol, 1996, 106 (6) :1260-1265.
  • 2Kanekura T, Chen X, Kanzaki T. Basigin ( CD147 ) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts [ J ]. Intern J Cancer,2002,99 (4) :520-528.
  • 3Menashi S, Sereva M, Ma L,et al. Regulation of extracellular matrix metalloproteinase expression by amphiregulin in transformed human breast epithelial cells [ J ]. Cancer Res,2003,63 ( 22 ) :7575-7580.
  • 4Major TC, Liang L. Lu X, et al. Extracellular matrix metalloproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma[ J]. Arterioscler Thromb Vasc Biol,2002,22(7):1200-1207.
  • 5Virmani R, Burke AP, Farb A, et al. Pathology of the vulnerable plaque [ J ]. J Am Coll Cardiol,2006,47 ( 8 suppl) : C13-18.
  • 6Schmidt R, Bultmann A, Ungerer M,et al. Extracellular matrix metallopmteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells : implications in acute myocardial infarction [ J ]. Circulation,2006,113 (6) :834 -841.
  • 7Galis ZS,Surhova GR, Lark MW, et al. Increased expression of matrix metalloproteinases and matrix degraded activity in vulnerable regions of human atherosclerotic plaques[ J]. J Clin Invest, 1994,94:2493-2503.
  • 8Sluijter JP, Pulskens WP, Schaneveld AH, et al. Matrix metalloproteinase 2 is associated with stable and matrix metalloproteinases 8 and 9 with vulnerable carotid atherosclerotic lesions[ J]. Stroke,2006,37 ( 1 ) :235-239.
  • 9Ikeda U, Shimada K. Matrix metalloproteinases and coronary artery diseases [ J]. Clin Cardiol,2003,26(2) :55-59.
  • 10Zhang JF, Ge H. Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells [ J ]. Intern J Cardiol,2007,117 ( 3 ) :373-380.

同被引文献49

  • 1张伟丽,宋雷,陈宇,刘继斌,吴永健,惠汝太.急性冠脉综合征的药物基因组学研究进展[J].中国分子心脏病学杂志,2011,11(4):251-256. 被引量：2
  • 2涂悦,周欣,姚旻,朱勇,庞伟,李玉明.广谱基质金属蛋白酶抑制剂对高血压性脑卒中影响的实验研究[J].中华高血压杂志,2006,14(9):730-734. 被引量：5
  • 3柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量：2149
  • 4Kanekura T, Chen X, Kanzaki T. Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts[J]. Int J Cancer, 2002,99:520-528.
  • 5Major TC, Liang L, Lu X,et al. Extracellular matrix metalloproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma [J]. Arterioscler Thromb Vasc Biol, 2002,22 : 1200 -1207.
  • 6Yoon YW, Kwon HM, Hwang KC, et al. Upstream regulation of matrix metalloproteinase by EMMPRIN, extracellular matrix metalloproteinase inducer in advanced atherosclerotic plaque[J]. Atherosclerosis, 2005,180 : 37-44.
  • 7Cipollone F, Fazia M, Iezzi A, et al. Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity[J]. Circulation, 2004,109 : 1482-1488.
  • 8Park EK, Jung HS, Yang HI, et al. Optimized THP 1 differentiation is required for the detection of responses to weak stimuli[J]. Inflamm Res, 2007,56 : 45- 50.
  • 9Eldika N, Yerra L, Chi DS, et at. Atherosclerosis as an inflammatory disease: implications for therapy[J]. Front Biosci, 2004,9: 2764-2777.
  • 10McEver RP. Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation[J]. Thromb Haemost, 2001,86 : 746-756.

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心血管病学进展
2009年 第1期

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