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儿童支气管哮喘的免疫疗法及其进展 被引量:2

Progress of immtmotherapy for pediatric asthma
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摘要 支气管哮喘(哮喘)的免疫疗法分特异性和非特异性两类,特异性免疫疗法目前的进展主要集中于研究作用机制以及纯化优化变应原制剂这两个方面。随着哮喘分子及细胞免疫学机制研究的日益深入,各种新的非特异性免疫治疗策略也层出不穷,其中抗IgE单克隆抗体发展最为成熟,已获得美国食品药品管理局认可用于中、重度哮喘的治疗。其他如抗免疫刺激序列DNA疫苗、辅助T细胞2型细胞因子疗法和抗T细胞疗法等也陆续投入哮喘治疗的研究。该文对特异性免疫疗法和非特异性免疫疗法及其研究进展进行综合性评述,并总结免疫疗法的进一步发展方向。
出处 《国际儿科学杂志》 2009年第1期25-27,共3页 International Journal of Pediatrics
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