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液质联用技术在药物分析中的应用研究进展 被引量:15

Recent Development in the Application of Liquid Chromatography-Mass Spectrometry in Pharmaceutical Analysis
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摘要 液相色谱-质谱联用技术以其高分离能力,高灵敏度,和专属性强的优势,在药物成分的鉴定分析、药物代谢研究、中成药和保健品中非法添加化学药物成分的鉴定分析以及药物残留分析等方面得到广泛的应用。本文简要综述了近年来液质联用技术在药物分析中的应用,为进一步扩大应用提供参考。 Liquid chromatography-mass spectrometry is regarded as an important technology for many advantages such as high separating efficiency, good sensitivity and strong specifity. So it is widely used in analysis of drugs and metabolites, chemical medicine mixed illegally in Chinese medicine and drug residues. This paper briefly reviewed its application in pharmaceutical analysis, offering reference for further application.
出处 《中国药品标准》 CAS 2008年第6期443-446,共4页 Drug Standards of China
关键词 液质联用技术 药物分析 药物代谢 应用 liquid Chromatography-mass spectrometry (LC-MS) pharmaceutical analysis drug metabolism application
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