摘要
设计合成了结构简单的分子内电荷转移荧光传感分子1,3,4-噻二唑类衍生物(1),实现了水-乙醇(体积比1∶9)混合溶剂中Hg2+的荧光猝灭型选择性灵敏传感,荧光猝灭常数达5.5×105mol-1.L,Hg2+线性响应范围为5.0×10-6～5.0×10-5mol/L.基于等摩尔连续变化法、红外光谱和核磁滴定实验结果提出了传感分子1与Hg2+的1∶1型结合模式,其中1-位S原子和2-位胺N原子为Hg2+配位原子;结合光谱变化讨论了Hg2+结合显著增强分子内电荷转移的荧光猝灭机理.
A structurally simple 2-amino-5-（p-dimethylamino）phenyl-1,3,4-thiadiazole（1）was designed and synthesized as a high selective fluorescent chemosensor for Hg2＋ in H2O/EtOH（volume ratio 1∶9）solution.The selective quenching by Hg2＋ of the fluorescence of compound 1 was rationalized in terms of the formation of a nonfluorescent Hg2＋-1 complex with enhanced intramolecular charge transfer compared to compound 1 itself.The 1∶1 binding mode of compound 1 with Hg2＋by its S atom and N atom of C-2 NH2 was proposed on the basis of Job plots,IR,and 1H NMR titrations.A linear fluorescent response was found for Hg2＋ over 5.0×10^-6 to 5.0×10^-5 mol/L with a detection limit of 1.0×10^-7 mol/L.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2008年第12期2531-2534,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金(批准号:20425518,20835005)资助
关键词
荧光传感
荧光猝灭
1
3
4-噻二唑
Fluorescent chemosensor
Hg2＋
Fluorescence quenching
Intramolecular charge transfer
1,3,4-Thiadiazole
