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空腹血糖、糖化血红蛋白及超敏C反应蛋白在脑梗死急性期的临床意义 被引量:17

The clinical value of fasting blood glucose, glycosylated hemoglobin and high-sensitivity C-reactive protein in acute phase of cerebral infarction
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摘要 目的探讨急性脑梗死患者空腹血糖(fasting blood glucose,FBG)、糖化血红蛋白(glycosylated hemoglobin,HbA1c)和超敏C反应蛋白(high-sensitivity C-reactive protein,hs—CRP)联合测定的临床意义。方法105例急性脑梗死患者进行欧洲脑卒中(europ stroke score,ESS)评分,测定FBG、HbA1c、hs—CRP,按FBG、HbA1c水平分组,比较各组间指标差异。结果非糖尿病性高血糖组ESS评分低于正常血糖组(P〈0.01)和糖尿病性高血糖组(P〈0.05),且其hs—CRP水平高于正常血糖组(P〈0.01)和糖尿病性高血糖组(P〈0.05)。结论高FBG伴HbA1c正常的急性脑梗死患者hs—CRP水平高,病情重。 Objective To discuss the clinical value of combined determination of fasting blood glucose (FBG) ,glycosylated hemoglobin (HbA1c) and high-sensitivity C-reactive protein(hs-CRP) in patients with acute cerebral infarction. Methods 105 patients with acute cerebral infarction were scored using the standard of Europ Stroke Score( ESS), and the level of FBG, HbA1c and hs-CRP were measured. All the patients were divided into three groups,according to the level of FBG and HbA1c, and the index of three groups were compared. Results The hyperglycemic group without diabetes had lower ESS score than the group with normal blood glucose( P 〈 0. 01 ) and the group with hyperglycemia and diabetes( P 〈0. 05 ). Also the hyperglycemic group without diabetes had higher level of hs-CRP than the group with normal blood glucose( P 〈 0. 01 ) and the group with hyperglycemia and diabetes( P 〈 0. 05). Conclusion Patients with acute cerebral infarction associated with high FBG and high HbA1c had high hsCRP, and severe prognosis.
出处 《中国基层医药》 CAS 2008年第11期1844-1845,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 脑梗塞 血糖 血红蛋白A 糖基化 C反应蛋白质 Brain infarction Blood glucose Hemoglobin A, glycosylated C-reactive proteins
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