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肠道菌群调整对肝硬化病人血浆一氧化氮和内毒素水平影响 被引量:11

INFLUENCE OF ADJUSTED INTESTINAL MICROFLORA ON CHANGE OF PLASMA NITRIC OXIDE AND ENDOTOXIN LEVEL IN PATIENTS WITH CIRRHOSIS
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摘要 本实验给肝硬化病人服用抑制肠源性内毒素血症的药物丽珠肠乐,结果表明:服用丽珠肠乐一个月后,血浆NO水平显著下降(P<0.01),白蛋白合成增多,门脉压力下降,肝功能显著改善,利于腹水消退,减少并发症的产生。其机制可能与内毒素水平降低有关。 In this experiment BIFIDOBIOGEN were per as for patients with cirrhosis,which inhibited enterogenous endotoxiema.After a month of BIFIDOBIOGEN treatment, the resuts showed the level of NO were significantly lower(P<001) and portal venous pressure fall,while albumin synthesis higher and liver function improved apparently,compared with control. It might be benefit ascited extinction and reduce complication production.
出处 《中国微生态学杂志》 CAS CSCD 1998年第1期36-37,共2页 Chinese Journal of Microecology
关键词 肠道菌群 一氧化氮 内毒素 肝硬变 Intestinal microflora Nitric oxide Endotoxin
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  • 1Prof. Dr. S. J. Konturek MD,T. Brzozowski PhD,J. Majka MD,A. Szlachcic MD,K. Czarnobilski MD. Nitric oxide in gastroprotection by sucralfate, mild irritant, and nocloprost[J] 1994,Digestive Diseases and Sciences(3):593~600
  • 2Dr. F. J. Andrews PhD,C. Malcontenti-Wilson BSc,P. E. O’Brien MD. Protection against gastric ischemia-reperfusion injury by nitric oxide generators[J] 1994,Digestive Diseases and Sciences(2):366~373

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