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人参皂甙Rg1对脑缺血再灌注大鼠脑组织c-Fos蛋白表达的影响 被引量：4

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摘要 目的:探讨人参皂甙Rg1对脑缺血再灌注大鼠脑组织c-Fos表达的影响。方法:分别给大鼠注射人参皂甙Rg1 10、20、40 mg.kg-1,然后采用大脑中动脉闭塞方法建立脑缺血再灌注模型,应用免疫组化法检测脑组织缺血再灌注24h后c-Fos的表达。结果:与单纯缺血再灌注组相比,人参皂甙Rg1各组c-Fos表达明显降低(P<0.05)。结论:人参皂甙Rg1防治大鼠脑缺血再灌注损伤机制可能与抑制脑组织c-Fos表达有关,且以高剂量效果较好。
作者 包翠芬 刘霞
机构地区 辽宁医学院科学实验中心 辽宁医学院组胚教研室
出处 《数理医药学杂志》 2009年第1期76-77,共2页 Journal of Mathematical Medicine
关键词 大鼠 脑缺血 人参皂甙RG1 C-FOS
分类号 R915 [医药卫生—微生物与生化药学]
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参考文献5

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二级参考文献19

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共引文献44

同被引文献88

引证文献4

二级引证文献37

数理医药学杂志
2009年 第1期

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