摘要
目的:观察1,6-二磷酸果糖(FDP)治疗新生儿缺氧性心肌损害中对血钙的影响。方法:155例缺氧性心肌损害患儿按入院时间顺序随机分为两组,治疗组78例,在治疗原发病的基础上加用1,6-二磷酸果糖治疗,对照组77例,仅治疗原发病。抽取血样本比较两组低钙发生率。结果:1,6-二磷酸果糖治疗组低钙发生率64.10%,对照组低钙发生率15.58%,两组比较差异有统计学意义(χ2=38.01,P<0.05)。两组低钙病例的主要症状抽搐、呼吸急促、呕吐腹胀、浮肿消失时间等比较,t值分别为14.35、13.83、14.18、1.96,前3组比较P<0.05,差异有统计学意义。结论:1,6-二磷酸果糖可能导致新生儿低钙血症,且低钙血症症状消失时间延长。
Objective： To observe the blood calcium effect of fructose-1, 6-diphosphate （FDP） injection in treatment of newbom anoxic cardiac muscle harm. Methods： One hundred and fifty-five patients of neonates with an.oxie cardiac muscle harm were divided into two groups, 78 cases in the treatment group were treated with routine treatment and FDP, 77 eases of the control group were treated with routine treatment only. Incidence of hypoealcemia, which was determined by blood samples, was compared between the two groups. Results： The incidence of hypocalcemia in FDP group was 64.10%, and that in non-FDP group was 15.58%. It is significant in statistics between the two groups （X^2 = 38.01, P 〈 0. 05 ）. And there were also significant differrences in statistics between the two groups in the durations of main clinic symptoms such as convulsion, ecphysesis, vomiting and abdominal distention with values of t respectively amounted to 14.35, 13.83, 14.18 （P 〈0.05）. Conclusions： FDP may cause neonatal hypoealeemia, and the duration of its symptoms would be longer.
出处
《儿科药学杂志》
CAS
2009年第1期16-17,33,共3页
Journal of Pediatric Pharmacy
