摘要
维生素Ｂ１２（ＶＢ１２）模型分子［单腈六甲基－Ｎ－（３－咪唑基）丙酰胺钴啉酯高氯酸盐４ｂ—４ｆ］，在甲醇溶液中用酸性缓冲溶液处理生成５ｂ—５ｆ．通过测定不同ｐＨ的缓冲溶液中的ＵＶ－Ｖｉｓ谱，计算了Ｃｏ—Ｎ键的平衡常数，侧链氮原子与中心钴离子配位键的强弱次序为４ｄ＞４ｆ＞４ｃ＞４ｅ＞４ｂ．
Vitamin B 12 model molecule, dicyano hexamethyl N (3 imidazoly)propylamido cobyrinates perchlorate 4b—4f were synthesized and treated with acidic buffers in methanol, and the ring was opened to give compounds 5b—5f. UV Vis spectra were determined in buffers with different pH values, and equilibrium constants of Co—N bonds were calculated. The strength of coordination bonds between N atom in the side chain of cobyrinates and Co atom was in the order of 4d>4f>4c>4e>4b.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1998年第4期550-554,共5页
Chemical Journal of Chinese Universities
基金
国家教育委员会优秀年轻教师基金
