摘要
目的观察脉平片抗血栓、降脂、耐缺氧的药理作用。方法通过测定脉平片对实验性大鼠血栓模型血栓形成时间的影响,观察其抗血栓作用;建立大鼠高脂血症病理模型,观察脉平片的降脂作用;通过小鼠耐缺氧实验,观察脉平片的耐缺氧作用。结果脉平片3个剂量组均能够延长小鼠凝血时间,明显延长血浆凝血酶原时间、凝血酶原消耗时间及白陶土部分凝血活酶时间;脉平片高剂量组能够明显降低血清总胆固醇及三酰甘油含量,提高高密度脂蛋白胆固醇含量;脉平片3个剂量组常压下均能够提高小鼠低氧条件下的生存能力。结论脉平片有较好的抗凝、降脂及耐缺氧作用。
Objective To observe the pharmacological function about anti-clotting, lipid-reducing and anti-hypoxia of Maiping Tablets. Methods The experimental thrombus model of rats was made to observing anti-clotting function of Maiping Tablets. The high blood lipid syndrome model of rats was made to observing lipid-lowering function of Maiping Tablets. The mice anti-hypoxia experiment was taken to observing the function of hypoxia tolerance. Results Maiping Tablets could prolong dotting time, significantly decrease serum total and low-density lipoprotein cholesterol, increase high-density lipoprotein cholesterol, and increase the viability of laboratory mice under ordinary pressure. Conclusion Maiping Tablets has good effect of anticoagulation, lipid-reducing and anti-hypoxia.
出处
《中国中医药信息杂志》
CAS
CSCD
2009年第2期43-44,共2页
Chinese Journal of Information on Traditional Chinese Medicine
关键词
脉平片
抗血栓
降脂
耐缺氧
动物模型
MaipingTablets
anti-clotting
lipid-loweringing
anti-hypoxia
animal model
