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Ras/Raf/MEK/ERK通路靶点药物联合治疗新进展 被引量:15

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摘要 Ras/Raf/MEK/ERK通路的异常与肿瘤的发生密切相关,由于其导致细胞增殖失控和凋亡受阻,因此可作为肿瘤治疗的一个靶点。目前在研究各靶点单药疗效的同时,更多的研究侧重于将对应Ras/Raf/MEK/ERK通路各靶点的药物与一般的放化疗、其他靶点药物和内分泌治疗等联合应用,并且取得了一定的进展。
作者 孟丽君 姜藻
出处 《肿瘤》 CAS CSCD 北大核心 2009年第1期97-100,共4页 Tumor
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