摘要
目的探讨新生儿糖代谢紊乱的影响因素及防治措施。方法回顾性分析2004年1月-2007年5月本院NICU791例出现糖代谢紊乱患儿的临床资料。其中低血糖439例,高血糖275例,二者兼有77例。采用χ2检验及Logistic多元回归分析。结果综合2种统计学分析结果,与对照组比较,低血糖组差异具有显著性意义的因素分别为(按发生率高低):低出生体质量[258例(58.77%)]、窒息[217例(49.43%)]、酸中毒[146例(33.26%)]、低体温[128例(29.16%)]、孕母妊娠高血压综合征[83例(18.91%)]、肺炎[63例(14.35%)]、孕母胎盘异常[35例(7.97%)]、孕母糖尿病[17例(3.87%)]、败血症[10例(2.28%)];在高血糖组差异具有显著性意义的因素分别为:肺炎[98例(35.64%)]、窒息[129例(27.23%)]、低氧血症[61例(22.18%)]、败血症[24例(8.73%)];低血糖及高血糖兼有组差异有统计学意义的因素分别为:酸中毒[33例(42.86%)]、肺炎[27例(35.06%)]、孕母糖尿病[6例(7.79%)]。结论对于存在高危因素的新生儿应常规监测血糖,及时纠正血糖紊乱,以降低新生儿糖代谢紊乱发生率及其所致的脑损伤。
Objective To investigate the relative risk factors of glucose metabolism disorder in newborn infants. Methods Clinical information of 791 newborns suffered from glucose metabolism disorders who had been hospitalized in NICU from Jan. 2004 to May 2007 were analyzed retrospectively. Four hundred and thirty - nine cases presented with hypoglycemia,275 cases presented with hyperglycemia, and 77 cases presented with both hypoglycemia and hyperglycemia. Data of risk factors were processed with both x^2 test and muhiple Logistic regression analysis. Results The statistic analysis showed that low birth weight[258 cases（58.77% ） ] ,asphyxia[217 cases（49.43% ） ] ,acidosis [ 146 cases （ 33.26 % ） ], hypothermia [ 128 cases （ 29.16 % ） ], maternal gestational hypertension [ 83 cases （ 18.91% ） ], pneumonia [ 63 cases （ 14.35% ） ] ,anomaly of placental35 cases（7.97% ） ] ,maternal diabetes[ 17 cases（3.87% ） ] and septicaemia[ 10 cases（2.28% ） ] were significant hypoglycemia risk factors （ according to the level of morbidity ）. Pneumonia [ 98 cases （ 35. 64% ） ], asphyxia [ 129 cases （27. 23 % ） ], hypoxemia [ 61 cases （22.18 % ） ] and septic aemia [ 24 cases （8.73 % ） ] were significant hyperglycemia risk factors. Acidosis [ 33 cases （42.86%） ], pneumonia [ 27 cases （35.06%） ] and maternal diabetes [ 6 cases （7.79 % ） ] were significant risk factors for neonates with both hypoglycemia and hyperglycemia. Conclusion Dynamic monitoring of blood glucose concentration and reasonable adjustment is recommended for neonates with risk factors to lower morbility and mortality.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2009年第2期106-108,共3页
Journal of Applied Clinical Pediatrics
关键词
糖代谢紊乱
低血糖
高血糖
婴儿
新生
glucose metabolism disorders
hypoglycemia
hyperglycemia
infant,newborn
