摘要
优化盐酸小檗碱凝胶剂制备工艺处方。采用正交实验法,对HPMC浓度、PEG400用量和甘油用量三因素进行考查,测定药物溶出度。盐酸小檗碱凝胶剂最佳处方为:盐酸小檗碱0.5,HPMC2.0,PEG4001.0,甘油4.0,亚硫酸氢钠0.1。
To fiherate prescriptons of the Berberine Hydroehloride hydrogel.Orthogonal experimental design the dosage of PEG 400,Glycerol and consistency of HPMC in the prescriptions, and to get the releasing degree of effective drug.The best prescription is：Berberine hydrochloride 0.5, HPMC 2.0, PEG4001.0, Glycerol 4.0, hydrosulfite of sodium 0.1.
出处
《天津化工》
CAS
2009年第1期22-23,共2页
Tianjin Chemical Industry
关键词
盐酸小檗碱
凝胶剂
正交实验
berberine hydrochloride
hydrogel
orthogonal experiment
