摘要
目的探讨肺血栓栓塞症(PTE)患者的栓塞面积大小与合并的基础疾病的相关性。方法收集2002年1月～2007年8月于我院住院治疗的PTE患者的临床资料,着重分析栓塞面积和合并的基础疾病,对影响栓塞面积的因子进行单因素和多因素相关分析。结果50～70岁为PTE的发病高峰年龄段,女性50岁以后发病要高于男性。PTE患者合并的基础疾病依次为:高血压(HBP)(58.91%),深静脉血栓形成(DVT)(47.29%),高脂血症(30.10%),慢性阻塞性肺疾病(COPD)(21.71%),冠心病(CHD)(20.93%),房颤(AF)(10.85%)等。56.59%的PTE患者合并2个以上基础疾病,合并基础疾病种类的多少与PTE栓塞面积的大小无相关性。单因素χ2检验显示年龄(≤40岁、≥71岁)、近期手术、骨折病史,AF及DVT与大面积PTE的发生相关(P<0.05)。多因素非条件Logistic回归分析显示,AF及DVT是大面积PTE的独立危险因素(P<0.05)。结论年龄(≤40岁、≥71岁)、近期手术、骨折病史,AF及DVT与大面积PTE的发生相关,AF及DVT是大面积PTE的独立危险因素。
Objective To evaluate the correlation of embolism area and basis diseases in patients with pulmonary thromboembolism （PTE）. Methods 129 patients with PTE admitted and treated in our department from 2002 to 2007 were retrospectively reviewed. Close attention was paid to embolism area and basis diseases. Influencing factors were extrapolated with univariate analysis and then multivariate analysis. Results Among the 129 patients, the peak period of age was 50 - 70 years old, the numbers of female were higer than that of male after 50 years old. Complicating Basis diseases in patients with PTE were following in order： hypertension （HBP） （58.91% ）, deep venous thrombosis （DVT） （47.29%）, hyperlipemia （30. 10% ）, chronic obstructive pulmonary diseases （COPD） （21.71% ）, coronary artery disease （CHD） （20.93 % ）, atrial fibrilation （AF） （ 10. 85 % ） and so on. 56.59% patients with PTE had more than two basis diseases, there was no correlation between the number of basis diseases and embolism area. Univariate analysis showed that age （ ≤40years,≥71 years）, case history of operation and bone fracture, AF and DVT were significantly correlated with the occurrence of massive PTE （ P 〈 0. 05 ）. Multivariate analysis showed that AF and DVT were independent risk factors that determined the magnitude of embolism area （P 〈0. 05）. Conclusion Age （ ≤40years, ≥71years）, case history of operation and bone fracture,AF and DVT are significantly correlated with the occurrence of massive PTE ; AF and DVT are independent risk factors that determined the magnitude of embolism area.
出处
《临床肺科杂志》
2009年第3期309-311,共3页
Journal of Clinical Pulmonary Medicine
关键词
肺血栓栓塞症
深静脉血栓形成
房颤
大面积肺栓塞
pulmonary thromboembolism
atrial fibrillation
deep venous thrombosis
massive PIE
