摘要
目的:探讨茉莉花提取液对老龄小鼠的抗氧化作用。方法:将老龄小鼠随机分为老龄茉莉花提取液组和老龄生理盐水组,每组8只,另设8只青年小鼠作为青年生理盐水组,三组连续灌胃28d,1次/d,第29天处死小鼠,迅速取其心、脑组织测定超氧化物歧化酶(SOD)、丙二醛(MDA)的含量。结果:老龄茉莉花提取液组比老龄生理盐水组SOD的含量有显著升高(P<0.01),比青年生理盐水组低(P<0.01);老龄茉莉花提取液组比老龄生理盐水组MDA的含量有显著的降低(P<0.01),与青年生理盐水组无明显差异(P>0.05)。结论:茉莉花提取液对老龄小鼠机体能起到显著的抗氧化作用,具有一定的抗衰老作用。
Objective： To explore the antioxidant effect of jasmine extracts to the old mice. Methods： The old mice were randomly divided into two groups, the old-age jasmine-extracts group and the old-age NS group, each group had eight porcines, and took the eight youth mice as the youth NS group.Three groups animals had been poured into stomach with jasmine-extracts and NS for 28 days respectively, one time a day. On the 29th day,the mice were sacrificed and took its heart and brain away. To detect the content of SOD and MDA. Results： In the heart and brain tissues, the content of SOD in the old-age jasmine-extracts groups was significantly increased as compared with the old-age NS group （P〈0.01）,but it was lower than the youth NS group （P〈0.01）;the content of MDA in the old-age jasmine-extracts groups was decreased significantly as compared with the old-age NS group （P〈0.01）,but it had no significant difference with the youth NS group （P〉0.05）. Conclusion： The jasmine extracts can play the remarkable antioxidant effect and has certain anti-aging effect in the old age mouse.
出处
《中国医药导报》
CAS
2009年第5期17-18,共2页
China Medical Herald
