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无创正压通气治疗矽肺合并Ⅰ型呼吸衰竭临床研究

The Clinical Research About NIPPV In Treating Silicosis With Type I Respiratory Failure
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摘要 目的观察双水平无创正压通气(BiPAP)对矽肺合并Ⅰ型呼吸衰竭的疗效。方法将52例矽肺合并Ⅰ型呼吸衰竭患者随机分为治疗组(27例)和对照组(25例),比较两组治疗前后血气分析指标、心率、呼吸频率及血压变化。结果治疗组和对照组治疗结束时PaO_2升高,心率及呼吸频率减慢,与治疗前相比差异有统计学意义。治疗组与对照组相比PaO_2升高、心率及呼吸频率下降差异有统计学意义。结论双水平无创正压通气治疗矽肺合并Ⅰ型呼吸衰竭更有效提高PaO_2,降低呼吸频率及心率。并治疗组降低PaCO_2更明显,但未造成过度通气。 objective To observe the clinical effect of NIPPV in treating silicosis with Type Ⅰ respiratory failure.Methods Fifty-two silicosis patients with Type Ⅰ respiratory failure were divided into two groups( therapy group and comparison group).The blood gas analysis index sign.HR.RR,blood pressure were compared btween the two groups.Results compared before treatment ,two groups showed improving PaO2 and lowering HR, RR after treatment,the differences being statistically significant .the therapy group showed significantly more positive effect of lowering HR, RR and improving Pao2 than that of comparison group ,the differences between the groups being statistically significant .Conclusion NIPPV intervention can effectively improve paO2 ,lower HR and RR in treating silicosis with Type Ⅰ respiratory failiue .Tough therapy group show more positive effect of lowering PaO2 ,PaCO2 is at normal level.
出处 《疾病监测与控制》 2009年第2期83-84,共2页 Journal of Diseases Monitor and Control
关键词 双水平无创正压通气 矽肺 Ⅰ型呼吸衰竭 Non-invasive positive prrssure ventilation silicosis Type Ⅰ respiratory failure
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