摘要
目的了解我院非发酵菌感染的菌群分布及耐药情况。方法对我院2006年1月～2006年12月分离的359株非发酵菌,采用法国生物梅里埃API20NE进行细菌鉴定,K-B法做药敏试验,并用WHONET-5.4软件对药敏结果进行数据分析。结果共分离出病原菌1685株,其中非发酵菌359株,359株非发酵菌中铜绿假单胞菌分离率最高占53.2%,其次是鲍曼不动杆菌(25.1%)和嗜麦芽窄食单胞菌(7.8%)。非发酵菌感染部位以痰液(咽拭子)检出率最高占60.4%,其次是创面分泌物(32.9%)和尿(3.9%)。病区分布以老年病房最多占44.0%,其次是烧伤科(22.6%)和呼吸科(11.7%)。检出的非发酵菌对所监测的抗菌药物均有不同程度的耐药。结论非发酵菌的检出率高,且对抗菌药物呈多重耐药,临床医生应根据药敏结果合理使用抗菌药物,有效控制感染。
Objective To investigate the clinical distributions and the antimicrobial resistance of non-fermentative bacteria in our hospital.Methods 359 strains of non-fermentative bacteria were isolated from clinical samples between January 2006 and December 2006. The isolated bacteria were identified with API20NE identified test （API Inc. France） and Kirby-Bauer （K-B） test was used for the antibiotics suseeptivity test. The results of the resistance rates were analyzed through the WHONET-5.4. Results A total of 1685 strains of bacteria were isolated, among which 359 strains were non-fermentative bacteria. The isolation rate of Pseudomona aeruginosa was the highest （53.2%）, followed by Acinetobacter baumanii （25.1%）, and Stenotrophomonas maltophilia （7.8%）. 60.4% of non-fermenting bacteria were isolated from the sputum. The positive rate from secretions of surgical wounds and urine were 32.9% and 3.9%. The non-fermentative infections were also commonly involved with geriatric wards （44.0%）, burned patients units （22.6%） and respiratory wards （11.7%）. These bacteria had various resistance to all detected antibiotics.Conclusion Non-fermenting bacteria had high isolated rate and multi-antibiotic resistance, so to control the nosocomical infection antibiotics should be used correctly under the guidance osf susceptivity testing.
出处
《当代医学》
2009年第3期20-21,共2页
Contemporary Medicine
关键词
非发酵菌
感染
耐药性
Non-fermentative bacteria
Infection
Drng-resistance
