摘要
采用邻氨基酚为原料合成了一系列N-取代苯并噁唑啉酮类化合物和N-取代的苯并噁嗪啉酮类化合物,其化学结构经过1H核磁共振及元素分析确证。初步的生物活性试验结果表明,N-取代苯并噁唑啉酮类化合物具有一定的杀虫杀菌活性,其中化合物3b、4b、14b、19b在50mg/L浓度下对淡色库蚊的杀死率为100%,化合物20b、21b、24b、25b、26b、27b、30b在1000mg/L浓度下对朱砂叶螨的杀死率均达95%以上;N-取代苯并噁嗪啉酮类化合物具有良好的除草活性,如化合物3d,5d,6d,7d和8d在浓度为100mg/L时,对苋菜Ambrosia tricolor Linn的抑制率达90%。
A series of novel N-substituted benzoxazol-2-ones and N-substituted benzoxazinone derivatives were designed and synthesized by the stating material 2-amino phenol Their structures were confirmed by ^1H NMR and elemental analysis. The preliminary bioassay showed that N-substituted benzoxazol-2-ones had insecticidal and fungicidal activities. The mortality of compounds 3b, 4b, 14b, 19b to Culex pipiens pallens Coqjllett at the concentration of 50 mg/L reached 100%, The mortality of compounds 20b, 21b, 24b, 25b, 26b, 27b, 30 b to Tetranychus cennbarinus at the concentration of 1 000 mg/L was all upwards 95%. Well, N-substituted benzoxazinone derivatives had herbicidal activity. The inhibition rate of 3d, 5d, 6d, 7d and 8d toAmbrosia tricolor Lima at the concentration of 100 mg/L was up to 90%.
出处
《现代农药》
CAS
2009年第1期15-19,共5页
MODERN AGROCHEMICALS
基金
国家重点基础研究发展计划("973计划")项目(2003CB114401)
