摘要
目的:探讨青少年腹型肥胖与血压、血糖、血脂、胰岛素及尿酸的关系。方法:测定174名高中生的体质指数(BMI)、腰围、腰臀比、血压、血脂等指标,根据BMI及腰围分为3组:非肥胖组、非腹型肥胖组、腹型肥胖组。分析3组血压、血糖、血脂、胰岛素、尿酸的差异及与BMI、腰围的相关性。结果:与非肥胖组相比,非腹型肥胖、腹型肥胖组血压、血脂[除总胆固醇(TC)外]、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)及尿酸的差异均有显著性意义(P<0.05),且腹型肥胖组空腹血糖(FPG)及餐后2h血糖(2hPG)显著增高,非腹型肥胖组血糖无显著增高;与非腹型肥胖组相比,腹型肥胖组血压、2hPG、空腹胰岛素、HOMA-IR、三酰甘油(TG)均有显著增高(P<0.01)。BMI、腰围与血压、血糖、FINS、血脂(除TC外)、尿酸呈直线相关性,WC与血脂(除TC外)、FPG、尿酸的相关性高于BMI,与2hPG、FINS、血压的相关性低于BMI。结论:青少年腹型肥胖比非腹型肥胖具有更高的代谢综合征(MS)危险性,青少年腹部脂肪分布较BMI与血脂(除TC外)、FPG、尿酸关系更为密切。
Objective： To investigate the correlation of serum blood pressure, serum lipid, fasting glucose, 2-h postprandial glucose, fasting insulin and uric acid with abdominal obesity in adolescents. Methods： Altogether 174 high-school students （101 male, 73 female, age range： 17 - 21 years） were selected from Yangpu District of Shanghai and studied in the body mass index （BMI）, waist circumference, blood pressure, serum lipid, fasting glucose, 2 h postprandial glucose, fasting insulin and uric acid. Based on BMI and waist circumference, the subjects were divided into Group A （normal weight） , B （non-abdominal obesity） and C （abdominal obesity）. Results： Compared with Group A, increased SBP, DBP, TG, HDL-C, LDL-C, FINS, HOMA-IR and Ua were observed in Groups B and C, and significantly increased FPG and 2 h PG were noted in Group C （P 〈 0.05）. SBP, DBP, 2 h PG, FINS, TG, BMI and WC were markedly higher in Group C than in B （P 〈 0.01）. WC was more correlated with FPG, TG, HDL-C, LDL-C and Ua, but less correlated with 2 h PG, FINS, SBP and DBP than BMI. Conclusion ： Adolescents with abdominal obesity have a higher risk of metabolic syndrome （MS） than those with non-adonimal obesity. The distribution of adipose tissues is correlated more with serum lipid （except TC） , FPG and Ua than with BMI.
出处
《医学研究生学报》
CAS
2009年第2期173-175,共3页
Journal of Medical Postgraduates
基金
上海市科委计划项目课题基金资助(批准号:08411967100)
关键词
腹型肥胖
代谢综合征
危险因素
青少年
Abdominal obesity
Metabolic syndrome
Risk factor
Adolescent
