摘要
目的观察5-氨基酮戊酸光动力疗法(ALA-PDT)治疗复发性尖锐湿疣的临床疗效及复发率。方法65例复发性尖锐湿疣患者局部外敷5-盐酸氨酮戊酸(ALA)后,用波长635nm的氦氖激光照射疣体,每次20～40min,1次/ w,共治疗1～6次;对照组为55例初发尖锐湿疣患者,用传统CO_2激光常规治疗。比较两组的疗效及复发率。结果治疗组经1～6次治疗后疣体完全消退,无溃疡、尿道狭窄、感染等并发症,术后随访3个月复发7(10.77%)例。对照组经1～2次治疗后疣体全部清除,术后随访3个月复发26(47.27%)例,其中19(34.55%)例在1～3周内复发。结论ALA -PDT治疗尖锐湿疣疗效可靠、复发率低、耐受性好。
Objective To observe the clinical effect and recurrence of topical 5 - aminolevulinic acid - photodynamic therapy （ALA -PDT） in lesions of recurrent condylomata acuminate. Methods Sixty -five patients with recurrent condylomata acuminate were treated with topical ALA before 635nm helium - neon laser radiation for twenty to forty minutes. They were subjected to some treatments range from one to six. Fifty - five primary patients were treated with traditional CO2 laser radiation for 1 or 2 times to eliminate the lesions as control group. Results All the lesions vanished after treated by ALA - PDT for 1 to 6 times. No ulcer,urethrostenosis,infection was observed, sixty-five patients were followed up for three months, 7 cases（ 10, 77% ） had re- curred. All the lesions were eliminated after CO2 laser treatment 1 or 2 times, however 26 cases（47.27% ） patients had recurred in 3 months and 19 （34.55 % ） patients of them had recurred from 1 to 3 weeks after the treatment. Conclusion Results suggests that ALA - PDT is an effective, well tolerated and less recurrent treatment for condylomata acuminata.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2009年第2期99-100,共2页
The Chinese Journal of Dermatovenereology
