摘要
目的探讨临床上颈部淋巴结转移阳性的分化型甲状腺癌的患者,淋巴结转移的模式和规律。方法将40例分化型甲状腺癌患者的颈清扫标本(共42例)的淋巴结术中均按照颈部分区放置并送病理检查。统计患者的年龄、性别和肿瘤的直径大小。用单因素和多因素分析结合分析淋巴结转移特点和规律。结果平均淋巴结转移数目是6.2个。好发的转移部位依次是Ⅵ区(95.24%)、Ⅲ区(69.05%)、Ⅳ区(57.14%)、Ⅱ区(52.38%)和Ⅴ区(19.05%)。副神经以上区域检测到转移占患者总数的7.14%。肿瘤大小和淋巴结转移数目之间存在回归关系(P=0.02),病人年龄和淋巴结转移数目之间存在负相关关系(P=0.032)。结论分化型甲状腺癌的患者从颈Ⅱ区到Ⅵ区间存在很高的淋巴结转移率。甲状腺原发肿瘤的大小和患者年龄是影响甲状腺癌颈部淋巴结转移数目重要的独立因素。
Objective To explore the metastatic pattern in well-differentiated thyroid carcinoma（WDTC） patients with clinically positive nodes in neck. Methods A total of 42 neck dissection（ND） specimens in 40 patients with WDTC were allocated according to the neck partition during operation. The age, sex and tumor size were recorded. Data were analyzed with univariate and multivariate analysis. Results The mean number of metastatic lymph nodes in ND specimen was 6.2. The predominant site of metastasis was region Ⅵ （95.24%） ,followed by region Ⅲ （69. 05% ）, region Ⅳ （57. 14% ）, region Ⅱ（52.38%）, region Ⅴ （ 19.05% ）. Metastatic lymph nodes above the XI nerve were found in 7.14% of patients. A regression was found between size of primary tumor and number of metastatic lymph nodes （P = 0.02）. A negative correlation was found between age and the number of metastatic lymph nodes （P = 0.032）. Conclusion Patients with WDTC have high incidence of metastatic disease in region Ⅱ-Ⅵ .Thyroid tumor size and age of patients are the independent influential factors of the number of metastatic lymph nodes.
出处
《山西医科大学学报》
CAS
2009年第2期164-166,共3页
Journal of Shanxi Medical University
关键词
分化型甲状腺癌
颈部淋巴结
转移
well-differentiated thyroid carcinoma
cervical lymph node
metastasis
