摘要
目前国外已证实,配戴原虫污染的角膜接触镜以及角膜轻度擦伤是诱发棘阿米巴角膜炎的主要原因。棘阿米巴原虫的包囊对外界的抵抗力较强,临床上药物疗效不佳,常需角膜移植进行治疗,所以建立良好的动物模型对于该病的深入研究至关重要。在以往的研究中有通过多种方法建立大鼠、家兔棘阿米巴角膜炎动物模型的报道,但这些方法不符合该病的自然病程,明显限制了对该病的基础研究。本实验设计了新的棘阿米巴角膜炎动物模型,并对其临床经过与病理学改变进行了观察。
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2009年第2期175-177,共3页
Chinese Journal of Ophthalmology
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