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冠心病患者血清热休克蛋白90水平变化及意义 被引量：2

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摘要 目的:探讨冠心病患者外周血清热休克蛋白90(HSP90)的水平,比较不同冠心病类型及不同冠脉病变程度血清HSP90的水平差异。方法:选择冠脉造影确诊并分层的冠心病患者65例[稳定性心绞痛23例,急性冠脉综合征(ACS)42例,包括不稳定性心绞痛27例,急性心肌梗死15例];其中冠脉1支病变组20例,冠脉2支病变组23例,冠脉多支病变组22例;以正常人20例作为对照组。采用酶联免疫吸附分析(ELISA)方法检测血清HSP90水平。结果:ACS组血清HSP90水平较正常对照组与稳定性心绞痛组显著增高(P<0.05),冠脉造影2支及多支病变组血清HSP90水平较1支病变组显著增高(P<0.05)。结论:血清HSP90水平在各种冠心病类型间差异存在显著性且与冠脉病变程度有关。
作者 朱惠民 曾高峰
机构地区 湖南省郴州市第一人民医院急救中心 南华大学附属第二医院心内科
出处 《实用医学杂志》 CAS 北大核心 2009年第4期576-577,共2页 The Journal of Practical Medicine
关键词 冠状动脉疾病 热休克蛋白90 急性冠脉综合征
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献8

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共引文献9

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实用医学杂志
2009年 第4期

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