期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

甲状腺过氧化物酶抗体阳性对妊娠结局的影响 被引量：2

Effects of thyroid autoimmunity on pregnant outcome.
原文传递
导出
摘要 妊娠妇女中,甲状腺过氧化酶抗体(TPOAb)的阳性率为3%～10%。不孕妇女中TPOAb阳性率是否显著高于一般妇女目前还存在争议。甲状腺自身免疫异常(TAI)对妊娠结局可能产生负面影响,TAI人群流产率与早产率都高于对照组,这在未经选择的一般人群以及行人工辅助生殖(ARTs)的人群中均有研究支持。TAI的干预有静脉注入免疫球蛋白、甲状腺素替代治疗和硒治疗几种方式。每种干预方法的机制及疗效评价均需更多证据支持。 In pregnant women,positive rate of thyroid peroxidase antibody （TPOAb） is approximately 3% - 10%. It is still controversial whether thyroid antibody positive rate is higher in women undergoing artificial assistant reproductive technologies. TAI might have a negative effect on pregnant outcome,which has been proved in different groups of women. Intravenous immunoglobulin, thyroxin replacement therapy and selenium therapy have been used for TAI intervention. More evidence is needed to demonstrate mechanism and evaluate effect for each therapy.
作者 彭雯 王晓东 刘超
机构地区 南京医科大学第一附属医院内分泌科
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2009年第3期273-275,共3页 Chinese Journal of Practical Internal Medicine
关键词 甲状腺自身免疫 妊娠结局 thyroid autoimmune pregnant outcome
分类号 R5 [医药卫生—内科学]
  • 相关文献

参考文献19

  • 1蒋乐堂,杨建华,梅云风,胡伟.TRAb、TPOAb联检在甲状腺疾病诊治中的应用价值[J].中国实用内科杂志,2001,21(9):540-541. 被引量：10
  • 2Hollowell JG, Staehling NW, Flanders WD, et al. Serum TSH, T (4) ,and thyroid antibodies in the United States population ( 1988 to 1994 ):National Health and Nutrition Examination Survey ( NHANES Ⅲ ) [ J ]. J Clin Endocrinol Metab, 2002,87 ( 2 ) : 489 - 499.
  • 3Bjoro T,Holmen J,Kruger O,et al. Prevalence of thyroid disease, thyroid dysfunction and thyroid peroxidase antibodies in a large, unselected population. The Health Study of Nord-Trondelag (HUNT) [ J ]. Eur J Endocrinol, 2000,143 ( 5 ) :639 - 647.
  • 4O'Leary PC, Feddema PH, Michelangeli VP, et al. Investigations of thyroid hormones and antibodies based on a community health survey:the Busselton thyroid study [ J]. Clin Endocrinol (Oxf), 2006,64( 1 ) :97 - 104.
  • 5关海霞,李晨阳,李玉姝,范晨玲,滕颖,欧阳煜宏,丛琦,滕卫平.妊娠晚期妇女甲状腺疾病特点及甲状腺自身抗体变化的研究[J].中华妇产科杂志,2006,41(8):529-532. 被引量：39
  • 6Pop VJ,Wijnen HA,Lapkienne L,et al. The relation between gesrational thyroid parameters and depression: a reflection of the downregulation of the immune system during pregnancy? [ J ]. Thyroid,2006,16(5 ) :485 -492.
  • 7Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and phostpartum:an Endocrine Society Clinical Practice Guideline [ J ]. J Clin Endocrinol Metab, 2007,92 ( Suppl 8 ) : S1 - S47.
  • 8Negro R, Mangieri T, Coppola L, et al. Levothyroxine treatment in thyroid peroxidase antibody-positive women undergoing assisted reproduction technologies: a prospective study [ J ]. Hum Reprod, 2005,20(6 ) : 1529 - 1533.
  • 9Poppe K,Glinoer D,Toumaye H, et al. Assisted reproduction and thyroid autoimmunity: an unfortunate combination? [ J ]. J Clin Endocrinol Metab ,2003,88 (9) :4149 - 4152.
  • 10Poppe K, Velkeniers B. Thyroid disorders in infertile women [ J ]. Ann Endocrinol (Paris) ,2003,64 ( 1 ) :45 - 50.

二级参考文献10

  • 1王铸钢,唐金凤,陈春荣,李凤英,陈家伦.甲状腺过氧化物酶抗体对酶活性的影响[J].中华内分泌代谢杂志,1995,11(3):139-141. 被引量：5
  • 2Zubair B,Pierre C,Bernard CD,et al.Laboratory medicine practice guidelines.Thyroid,2003,13:123-126.
  • 3WHO/UNICEF/ICCIDD.Urinary iodine.In:Assessment of iodine deficiency disorders and monitoring their elimination:a guide for programme managers.2nd ed.Geneva:WHO,2001.31-36.
  • 4Greenspan FS.The thyroid gland.In:Greenspan FS,eds.Basic and clinical endocrinology.6th ed.New York:Lange Medical Books/McGraw-Hill,2001.201-272.
  • 5Shah MS,Davies TF,Stagnaro-Green A.The thyroid during pregnancy:a physiological and pathological stress test.Minerva Endocrinol,2003,28:233-245.
  • 6Muller AF,Drexhage HA,Berghout A.Postpartum thyroiditis and autoimmune thyroiditis in women of childbearing age:recent insights and consequences for antenatal and postnatal care.Endocr Rev,2001,22:605-630.
  • 7Haddow JE,Palomaki GE,Allan WC,et al.Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.N Engl J Med,1999,341:549-555.
  • 8Pop VJ,Kuijpens JL,Van Baar AL,et al.Low maternal free thyroxine concertration during early pregnancy are associated with impaired psychomotor development in early infancy.Clin Endocrinol,1999,50:149-155.
  • 9LaFranchi SH,Haddow JE,Hollowell JG.Is thyroid inadequacy during gestation a risk factor for adverse pregnancy and developmental outcomes? Thyroid,2005,15:60-71.
  • 10卢倜章.TSH受体抗体测定的临床意义[J].国外医学（放射医学核医学分册）,1999,23(5):203-205. 被引量：20

共引文献47

同被引文献25

  • 1陈士岭,何锦霞,宋华东,黎淑贞,刘晓宁,李红,邢福祺.应用四种用药方案进行冻融胚胎移植的临床结局比较[J].南方医科大学学报,2007,27(3):303-306. 被引量：40
  • 2Orvieto R, MeRcer S, Volodarski M, et al. Luteal phase support for patients undergoing frozen-thawed embryo transfer cycles--the required progesterone dose[J]. Clin Exp Obstet Gynecol, 2007, 34 (1): 25-6.
  • 3Bjuresten K, Landgren BM, Hovatta O, et al. Luteal phase progesterone increases live birth rate after frozen embryo transfer [J]. Fertil Steril, 2011, 95(2): 534-7.
  • 4Pabuccu R, Akar ME. Luteal phase support in assisted reproductive technology[J]. Curr Opin Obstet Gynecol, 2005, 17(3): 277-81.
  • 5Fatemi HM, Popovic-Todorovic B, Papanikolaou E, et al. An update of luteal phase support in stimulated IVF cycles [J]. Hum Reprod Update, 2007, 13(6): 581-90.
  • 6Tavaniotou A, Smitz J, Bourgain C, et al. Comparison between different routes of progesterone administration as luteal phase support in infertility treatments [J]. Hum Reprod Update, 2000, 6 (2): 139-48.
  • 7张以文.新型孕激素制剂地屈孕酮及其临床应用[C].第二届全国不育症研讨会.2007:4.
  • 8Schindler AE, et al. Classification and pharmacology of progestins [J]. Maturitas, 2008, 61(1-2): 171-80.
  • 9Chakravarty BN, Shirazee HH, Dam P, et al. Oral dydrogesterone versus intravaginal micronised progesterone as luteal phase support in assisted reproductive technology (ART) cycles: results of a randomised study [J]. J Steroid Biochem Mol Biol, 2005, 97(5): 416-20.
  • 10Patki A, Pawar VC. Modulating fertility outcome in assistedreproductive technologies by the use of dydrogesterone[J]. Gynecol Endocrinol, 2007, 23(Suppl 1): 68-72.

引证文献2

二级引证文献25

中国实用内科杂志
2009年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部