摘要
目的:观察茉莉花提取液对家兔离体小肠收缩活动的影响,并探讨其作用机制。方法:采用离体肠段实验法,应用0.25g/ml、0.33g/ml、0.50g/ml三种不同浓度的茉莉花提取液,观察其对离体小肠收缩活动的影响和0.33g/ml茉莉花提取液对乙酰胆碱的拮抗作用。结果:不同浓度的茉莉花提取液均能使小肠收缩曲线与基线构成的面积减小,浓度为0.33g/ml时作用最明显,但对收缩频率无明显影响,且0.33g/ml茉莉花提取液能使乙酰胆碱作用下的小肠收缩幅度减小。结论:茉莉花提取液能抑制家兔离体小肠收缩活动,并对乙酰胆碱有一定的拮抗作用。
Objective： To observe the effect of the extract of Jasmine on contractile activity of isolated small intestine of rabbits and explore its mechanisms. Methods： The experiment of isolated intestine was used to observe the effect of the extract of Jasmine of three different concentrations of 0.25 g/ml, 0.33 g/ml and 0.50 g/ml on isolated small intestine and the extract of Jasmine of 0.33 g/ml on the acetylchohne. Results： All extracts of three concentration could reduce the size of contraction curve and the baseline of isolated small intestine, especially the 0.33 g/ml, but had no significant impact on the frequency of contraction. Extracts of 0.33 g/ml Jasmine could lessen range contraction of isolated small intestine under acetylcholine. Conclusion： The extract of Jasmine could inhibit contraction of isolated small intestine of rabbits, and has some antagonistic effect on acetylcholine.
出处
《中国医药导报》
CAS
2009年第6期18-19,共2页
China Medical Herald
关键词
茉莉花
离体小肠
收缩活动
乙酰胆碱
Jasmine
Isolated small intestine
Contraction
Acetylcholine
