摘要
目的验证用激光诱发荧光光谱分析方法诊断结肠癌的可行性。方法使用氮分子激光器（波长３３７ｎｍ）和光学多道分析仪（ＯＭＡⅢ），收集结肠癌术后标本的激光诱发荧光光谱。用已总结出的结肠癌的激光诱发荧光光谱判别标准，对５１例结肠标本的光谱进行分析判定，并与病理结果比较。结果与病理结果比较，判别标准诊断结肠癌的敏感性为８０．０％，特异性为１００％，阳性预示值为１００％，阴性预示值为８３．９％，诊断符合率为９０．２％。结论结肠癌的激光诱发荧光光谱判别标准诊断结肠癌是可行的。
Objective To study the usefulness of laser induced fluorescence (LIF) spectrum for diagnosis of colon cancer. Methods Nitrogen laser, wavelength 337nm, optical multichannel analyzer (OMA Ⅲ) were used to demonstrate LIF spectra. A standard spectrum of LIF of colon cancer was used to analyse that of 51 surgically removed colon specimens and the results were compared with pathological findings. Results Compared with pathological findings, LIF spectrum examination had 80.0% sensitivity, 100% specificity, with positive predictive value of 100%, negative predictive value of 83.9% and accuracy of 90.2% for the diagnosis of colon cancer, respectively. Conclusion Laser induced fluorescence (LIF) spectrum of colon is of use in the diagnosis of colon cancer.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1998年第1期76-77,共2页
Chinese Journal of Oncology
关键词
结肠肿瘤
诊断
激光诱发荧光
Colonic neoplasms/diagnosis Laser induced fluorescence
