摘要
目的世界首例小儿腹腔镜下根治性膀胱切除全去带乙状结肠原位新膀胱术的经验及疗效。方法3岁男孩,确诊为膀胱横纹肌肉瘤,行腹腔镜下根治性膀胱切除术全去带乙状结肠新膀胱术。手术包括先行腹腔镜下双侧盆腔淋巴结清扫及膀胱切除,下腹部小切口取出标本,再行去带乙状结肠原位新膀胱术。结果手术成功完成,手术时间为6h,其中腹腔镜根治性膀胱切除部分时间约3.5h。术中出血量约50ml,术中输入200ml浓缩红细胞以确保手术安全性。双侧盆腔淋巴结各清扫6个,均为阴性,术中输尿管及尿道切缘均为阴性。患儿术后3d恢复肠蠕动。盆腔引流管于术后7d拔除,新膀胱造瘘管于术后14d拔除,术后25d行经尿道膀胱造影,确定无造影剂外漏后拔除导尿管及双侧输尿管支架管。患儿拔除导尿管后1周左右基本恢复白天控尿及排尿功能。5个月后复查,提示新膀胱容量约为110ml,膀胱残余尿量约10ml,最大尿流率约12ml/s。围手术期未见明显水电解质及酸碱平衡紊乱,无尿漏、输尿管返流及肠梗阻发生。结论随着手术经验的丰富和技术的发展,腹腔镜下根治性膀胱切除术具有损伤小,术中出血少,患儿恢复快等优点,有望成为治疗小儿膀胱癌的安全可靠的方法。
Objective To present a case of laparoscopic radical cystectomy and detenial sigrnoid colon orthotopic neobladder reconstruction for bladder tumor in a child. Methods A 3-year-old boy with bladder rhabdomyosarcoma underwent laparoscopic radical cystectomy and detenial sigrnoid colon orthotopic neobladder reconstruction. The bilateral pelvic lymphadenectomy and eystectomy were performed laparoscopically, and removal of the mobilized specimens and urinary diversion operation were managed through enlarged abdomen incision. The urinary diversion procedure included construction of the detenial sigmoid pouch, bilateral stented antiflux implantation of the ureters in the pouch and orthotopic anastomosis of the neobladder with the urethra. Results The total operative time was 6 h, and the laparoscopic procedure lasted for about 3.5 h. The intraoperative blood loss was 50 ml, and 200 ml concentrated red blood cell transfusion was used for the safety of the patient. Six dissected lymph nodes in each pelvic side and the surgical margins of the ureter and urethra were all free of tumor invasion. Bowel peristalsis recovered 3 days after the operation, and the pelvic drainage and the neobladder drainage tubes were removed on day 7 and 14, respectively. The urethral catheter and ureteral stents were removed 25 days after the operation. The daytime urine control and micturition recovered 1 week after the operation. The neobladder capacity was about 110 ml, with residual urine volume of 10 ml and peak flow rate of 12 ml/s after 5 months. No perioperative complications occurred such as water-electrolyte and metabolic acid-base balance disorders, urinary leakage, reflux or bowel obstruction. Conclusion Laparoscopic radical cystectomy is minimally invasive, reduces intraoperative blood loss and allows rapid postoperative recovery, and can be a promising approach to management of bladder rhabdomyosarcoma in children.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2009年第1期105-108,共4页
Journal of Southern Medical University
