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简化局部枸橼酸抗凝方法在连续性肾脏替代治疗中的应用 被引量:4

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摘要 目的观察简化的局部枸橼酸抗凝(RCA)技术在连续性肾脏替代治疗中的应用效果。方法实验分为局部枸橼酸抗凝组(RCA组)和小剂量肝素抗凝组(对照组)。各行CVVH30例次,治疗时间8~12h。于治疗前、治疗2、4、8h、治疗后等时间点监测全血活化凝血时间(ACT)、血清游离钙(iCa)、血酸碱度(PH)、碳酸氢根(HCO3^-)、血清钠(Na^+)等指标。结果与对照组比较.RCA组体外抗凝达到有效水平,能长时间维持,治疗效率不受影响;RCA组患者临床无出血或出血加重情况;体内电解质、酸碱度等均能维持在正常范围之内。结论改进后的枸橼酸抗凝方案的操作简便,抗凝效果肯定,安全性良好,临床切实可行。
出处 《中国医师杂志》 CAS 2009年第2期254-256,共3页 Journal of Chinese Physician
基金 湖南省卫生厅科研基金资助项目(2004-034) 湖南省自然科学基金资助项目(03jjy3049)
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参考文献5

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二级参考文献14

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