摘要
Ｎ氨甲酰基Ｄ苯甘氨酸不对称热水解反应的研究江宁贺鹏卢大军强亚静杨柳孙万儒（中国科学院微生物研究所北京１０００８０）Ｄ苯甘氨酸是半合成β内酰胺类抗生素的重要原料，它的合成主要是从５苯基海因出发，经海因酶开环生成Ｎ氨甲酰基Ｄ苯甘氨酸后，...
NcarbamoylDphenylglycine could be hydrolyzed to obtain Dphenylglycine by heating under weak acid or basic condition.Experimental results showed that the reaction was first order kinetically.It was effected by pH.The specific rotation D20 of purified product Dphenylglycine was153(C=1,1NHCl).The discovery of the reaction should open a new way to synthesis optical active amino acids.
出处
《生物工程学报》
CAS
CSCD
北大核心
1998年第2期220-223,共4页
Chinese Journal of Biotechnology
