摘要
目的评估短暂性脑缺血发作（TIA）发病7d内动脉粥样硬化性血栓性事件（AT）。方法应用ABcD2评分回顾性研究符合本研究入选标准的198例TIA临床资料，根据评分分为低危组（≤3分）和中-高危组（≥4分），分别统计TIA发病7d内AT事件的发生率、种类及危险因素，并在两组间进行卡方检验。结果既往病史依次为高血压病、糖尿病、冠心病、脑梗死和高脂血症，低危组TIA发病7d内AT事件发生率为6．19％（6／97例），均为TIA复发；中-高危组为14．85％（15／101例），其中TIA复发2例、缺血性卒中10例、TIA复发＋缺血性卒中1例、心绞痛1例、心肌梗死1例，两组均无周围性血管病以及血管病性死亡；中-高危组TIA后7d内AT事件明显多于低危组（51．70％比27．27％，P〈0．05）。结论ABcD2评分≥4分的TIA病人在发病后7d内有更高的发生AT事件的风险。
Objective To assess the incidence, types and risk factors of atherothrombotic events （AT） within 7 days after transient ischemic attack （TIA） with ABCD2 Score in Chinese patients. Methods With ABCD2 Score, we retrospectively reviewed the medical records of 198 TIA patients , which met the inclusion criteria of our study. They were divided into a low risk group （ABCD2 ≤3 ） and a moderate-high risk group（ABCD2≥4） and the incidence, types and risk factors of AT within 7 days after TIA were evaluated and compared respectively with Χ^2 test between the two groups. Statistic significance was considered as P 〈 0. 05. Results The order of the frequency of accompanying diseases was hypertension 68. 18% （ 135/198 ）, diabetes 23.74% （ 47/198 ）, coronary artery disease 21.72% （ 43/198 ）, ischemic stroke 15.66% （31/198） and hyperlipemia 12. 63% （25/198）. AT within 7 days after TIA was observed in 6. 19% （6/97） of the patients in the low risk group, all of them were suffering from TIA recurrence. In the moderate-high risk group, 14. 85% （ 15/101 ） of the patients experienced AT, including 2 cases of TIA recurrence, 10 cases of ischemic stroke, 1 case of both TIA recurrence and ischemic stroke, 1 case of angina pectoris and 1 case of myocardial infarction. There was no peripheral vascular disease or death from vascular disease. Incidence of AT within 7 days in the moderate-high risk group was significantly higher than that in the low risk group （51.70% vs 27.27%, P 〈 0. 05 ）. Conclusion TIA patients with ABCD2 ≥ 4 are at higher risk of AT within 7 days after TIA onset.
出处
《中华内科杂志》
CAS
CSCD
北大核心
2009年第3期213-215,共3页
Chinese Journal of Internal Medicine
