摘要
采用病理解剖、冰冻切片、HE染色法,对伪狂犬病病仔猪的大脑、肝、肾、脾、淋巴结等组织进行了组织病理学观察。结果显示:大脑脑膜肿胀,小血管扩张充血,神经胶质结节,神经元和胶质细胞核内可见嗜酸性包涵体;肝实质坏死灶内分布大量蓝紫色坏死崩解的细胞核碎粒,肝小叶的肝索紊乱、断裂,肝窦扩张充满大量血液,肝细胞肿大,多发生水泡变性;脾脏组织结构疏松,有许多分界清晰的坏死灶,脾小体数量减少;红细胞、淋巴细胞数目减少,网状细胞增生。肾小管上皮细胞脱落,发生颗粒变性,仅残留上皮细胞的基膜呈条索状排列,肾小球内和肾间质内出血;淋巴结肿胀,被膜疏松,毛细血管数量增多,坏死组织内有大量含铁血黄素晶体颗粒存在,淋巴细胞内有嗜酸性核内包涵体。
The materials including the brain, liver, kidney, spleen, lymph nodes of pigs that were diagnosed to be pseudorabies disease were observed by the freezing sections and HE dyeing. Histopathological changes demonstrated the following symptoms： Swollen meninges, dilatate and congested capillary vessel, parts of glial cells formed nodules, and eosinophilic inclusion can be seen in the neurons and the glial cells. An amount of blue-violet broken pieces of the nucleus and swollen hepatic cell with vacuolar degeneration can be seen in the necrosis focus of the liver. The hepatic cord in lobules of liver was in disorder. The spleen structure becomes loose with limpid necrsis focus. The splenic nodul and lymphocute decreased and reticular cell got hyperplasia. Epithelia of nephric tububle showed desquamation and granular degeneration with residual cordlike basement membrane. Lymph node swelled, a large number of hemosiderin crystal particles were found in the swollen lymph nodes. Eosinophilic inclusion can be seen in the lymphocute.
出处
《贵州农业科学》
CAS
北大核心
2009年第3期106-107,110,共3页
Guizhou Agricultural Sciences
关键词
猪
伪狂犬病
病理组织学
包涵体
pig
pseudorabies
histopathological
inclusion
