摘要
目的临床分析耐多药病例初治、复治抗结核治疗的效果。方法采取回顾性分析方法,选择耐多药病例40例,分初治、复治组,组间比较用χ2检验。结果初治、复治组疗程结束时痰菌阴转率、肺部病灶吸收率、肺部空洞闭合及缩小率分别为:87.5%,66.7%;75.0%,62.5%;69.2%,54.5%。两组间无显著性差异。结论对初治耐多药病例应选择一线抗结核药物的标准方案,复治耐多药病例应根据既往抗结核药物用药史,药物敏感试验结果选择个体化治疗方案。
Objective To analyze the clinical curative effect of anti-tubercular treatment （ATT） in initial treating and retreating pulmonary multi-drug resistant tuberculosis （MDR-TB） patients. Methods 40 cases with pulmonary MDR-TB, selected and divided into initial treating group and retreating group, were retrospectively studied and the results were statistically analyzed by χ^2 test. Results The rates of TB-sputum negative reaction, absorption, cavity healing and diminution of the initial treating group and retreating group were respectively 87.5 % and 66. 7 %, 75.0% and 62.5 %, 69. 2% and 54. 5 % by the end of the treatment course, which showed no significant differences between these two groups. Conclusion The standard therapy with the first line anti-tuberculosis drugs should be applied to the initial treating patients with MDR-TB, while the retreating patients should be given individual therapies according to the history of ATT medication and the results of drug susceptibility testing.
出处
《临床肺科杂志》
2009年第4期471-472,共2页
Journal of Clinical Pulmonary Medicine
关键词
肺结核
耐多药
初治/复治
pulmonary tuberculosis
multi -drug resistant
initial treating/retreating
