摘要
目的探讨重组人干扰素α-1b对慢性乙型病毒性肝炎抗病毒的临床治疗效果。方法选择45例慢性乙型肝炎患者为治疗组,另设同期接诊的42例慢性乙型肝炎患者为对照组,治疗组给予干扰素α-1b500万U,对照组给予口服维生素及一般护肝药物,疗程均为6个月,两组病例在治疗前和治疗结束后检测HBV-M、HBV-DNA、肝功能。结果治疗组HbeAg和HBV-DNA转阴率分别为42.22%和46.66%,显著高于对照组。结论干扰素α-1b具有明显的清除和抑制乙型肝炎病毒的作用。
Objective To study the clinical effect of Interferon-1b in the treatment of the chronic hepatitis B. Methods Choose 45 cases of patients with chronic hepatitis B for the treatment group, a separate reception in the same period 42 patients with chronic hepatitis B patients in the control group,treatment group given interferon α-1b 500 million U,in the control group given oral vitamin and general liver-aid medicines,treatment of 6 months,patients in both groups before treatment and treatment after the detection of HBV-M,HBV-DNA,liver function. Results After treatment,HBeAg and HBV-DNA negative rate is separately 44.22 percent and 46.66 percent in the Interferon-2b group,effectiveness ratio of Interferon-2b is superior to that of control group. Conclusion Interferon-lb can effectively inhibit and eliminate the hepatitis B virus.
出处
《中国现代医生》
2009年第7期62-63,共2页
China Modern Doctor
关键词
于扰素
慢性乙型肝炎
抗病毒
疗效观祭
Interferon
Chronic hepatitis B
Antivirus
Curative effect observation
