摘要
用溶液共混法和冷冻解冻工艺制备聚乙烯醇(PVA)/聚乙烯基吡咯烷酮(PVP)二元复合水凝胶,通过红外、XRD、DSC、含水率与溶胀测试等对材料的结构与性能进行分析表征,并研究了材料的力学性能与细胞毒性。结果表明,PVP能与PVA通过化学键合形成分子级混合的PVA/PVP复合水凝胶。PVP含量可以影响PVA水凝胶的结构、结晶度、玻璃化转变温度、吸水率以及力学性能。该复合水凝胶具有高的吸水率和良好的细胞相容性,而且具有类似天然软骨的可渗透性。PVP/PVA复合水凝胶是一种有发展前景的人工软骨替代材料。
The poly（vinyl alcohol）/poly（N-vinyl pyrrolidone） （PVA/PVp） hydrogels were prepared by co-solution method and treated with repeated freezing-thawing recycle. The composite material was analyzed by infrared spectroscopy,X-ray diffraction, differential scanning calorimeter. Its water absorption, mechanical property and cytotoxicity were also tested. The results show that PVP can chemically bond with PVA and form composite hydrogel with PVA in molecular level. The content of PVP can affect the structure, crystalinity,glass transition temperature, water absorption and mechamical property of PVA hydrogel. The PVP/PVA hydrogel has high water content and good cytocompatibility. It is a permeable material similar to natural cartilage,which is a promising artificial cartilage material.
出处
《功能材料》
EI
CAS
CSCD
北大核心
2009年第3期439-442,共4页
Journal of Functional Materials
基金
国家重点基础研究发展计划(973计划)资助项目(2007CB936102)
关键词
聚乙烯醇
聚乙烯基吡咯烷酮
水凝胶
人工软骨
poly（vinyl alcohol）
poly（N-vinyl pyrrolidone）
hydrogel
artificial cartilage
