摘要
目的:探讨静脉注射三七总皂甙对兔创伤性深静脉血栓形成的影响。方法:按随机原则分为三七总皂甙预防组、低分子肝素钠预防组、动物模型对照组,每组10只兔。两预防组于造模后第2天每天给药,持续8d。作相关血液流变学指标检测及记录各组血栓形成情况,并作统计学分析。结果:三七总皂甙及低分子肝素钠皆有较好的降低血液粘度及改善血液"高凝状态"的作用。结论:三七总皂甙与低分子肝素钠同样具有减少创伤性下肢深静脉血栓形成的作用。
Objective： To study the influence of radix notoginseng total saponins （RNTS） injection on lower--extremity traumatic deep venous thrombosis （TDVT）. Methods： Thirty rabbits were randomly divided into 3 groups （n= 10 each）： RNTS preventive group, low--molecular--weight heparin sodium （LHS） preventive group and model group. Two days after TDVT modeling, the 2 preventive groups were given RNTS and LHS injection respectively for 8 days. The related haemorheology indexes were measured and statistically analyzed. Results： Both preventive groups obviously decreased blood viscosity and improved blood hypercoagulable state. Conclusion： RNTS has the same preventive effect on TDVT as LHS does.
出处
《中国中医骨伤科杂志》
CAS
2009年第3期15-17,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
下肢深静脉
血栓
三七总皂甙
低分子肝素钠
动物实验
Lower--extremity deep venous thrombosis
Radix notoginseng total saponins
Low--molecular--weight heparin sodium
Experimental study
Animal experiment
